Molecule 2-DG vs childhood cancer

• April 26, 2024

The alveolar rhabdomyosarcoma it's a kind of Cancer that affects children and adolescents, and represents 5% of pediatric tumors. Spanish scientists, of the Biomedical Research Institute of Bellvitge (IDIBELL), they discovered a molecule that would help in the treatment against this condition.

According to the study, published by the magazine Cancer Research , the particle, called 2-deoxyglucose(2-DG), generates the death of tumor cells by inhibiting the metabolism of glucose used for that disease. Another benefit is to stop the growth and development of the disease.

"The 2-DG It is very similar to the molecule used in positron emission tomography (PET), an imaging technique used to diagnose various tumors according to your consumption rate of glucose ", The researchers point out.

The only known treatment for this condition is the surgery due to the ineffectiveness of chemotherapy . In addition, the survival rate at five years after diagnosis is 70%.

What is the Rhabdomyosarcoma?

This cancerous tumor affects the muscles that are attached to the bones . The places where it is recorded most frequently are the head , the neck , the genitourinary system , The arms and the legs.

The origin of the disease is still unknown, however, children with congenital anomalies they are the most likely to acquire it. The symptom that present vary according to the place where the tumors are located; Among the most common are: bleeding, nasal congestion, problems swallowing, inflammation around the eyes, vision damage and painful bumps on the arms.

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