Being hungry blocks bad memories

• April 26, 2024

Two studies carried out on fruit flies by researchers of the National Center for Scientific Research (CNRS) of France and the Institute of Medical Science of Tokyo (Igakuken) , show that when these animals come to have hungry , but not resources, your brain blocks the formation of bad memories.

The researchers found that when the fruit flies, dorsophilites, come to have hungry in excess, but resources are scarce, their brains specifically disconnect the formation of long-term memory of negative memories, which depends on the synthesis of more expensive energy proteins.

Several neurons affect this process of preserving bad memories or those that require repetitive learning. At the same time, having hungry , in their brains the production of pleasurable memories in the long term is enhanced.

When energy is scarce and survival is threatened, the brain takes precedence over other organs and deactivates all its functions in order to save resources, explain the study authors. CNRS, Pierre-Yves Plaçais and Preat Thomas , according to very interesting

"The hungry flies store memories better than the satiated flies, because that hungry state makes them ready to initiate the expression of the necessary genes in the formation of long-term memory," he explains. Minoru Saitoe, from the Institute of Medical Science in Tokyo.

Focused on a lighter food deprivation, this research shows that, in reality, a slight fast increases the long-term memory formation of memories, both negative and pleasant.

In this regard, they observed that when the fruit flies were becoming more and more deprived of food, their capacity to form negative memory diminished, while the formation of pleasant memories continued to increase as the hungry .

This is due to the fact that the satiated and hungry flies use different mechanisms to form long-term memory. Specifically, while the satiated ones use a transcription factor CBP, but having hungry, flies use another factor called CRTC, which affects the type of memories.

In this way, we continue to study the similarities between the functioning of the brain of different animals with that of people, when it comes to having hunger and satiety , as well as the network of neurons involved in various areas involved, as in the hippocampus.

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