What causes us to feel bad about getting sick

One of the signals that our body sends when we get sick is that we feel low energy , we do not even want to get out of bed . This is particularly emphasized in those patients who suffer from chronic diseases since their motivating behavior, such as energy expenditure, are totally compromised.

Until now it is known that all mammals, including humans, focus all their energy on combatingdiseases . A) Yes the body uses a series of strategies such as lethargy, fever and lack of appetite, leaving aside biological and physiological needs to restore health.

Previous studies have already identified the neurotransmitters (specialized cells in the brain) responsible for fever and lack of appetite, but the cause of the low in the physical activity and the motivation They were uncertain, until now.

 

Orexine, responsible for the lack of activity

According to an investigation by Oregon Health and Science University Doembecher Children's Hopsital, there is signaling system in the brain, regulator of sleep, which is also responsible for inducinglethargy during the chronic diseases.

This study published in Journal of Neuroscience It is very important because it implies that new drugs made to treatsleep disorders can, likewise reverse the lack of activity Y exhaustive feeling in an acute illness.

To determine the cause of lethargy, Marks and his team of collaborators studied rat brains; found that inflammation occurs in the area near theneurotransmitter system, responsible for physical activity and reward, known as theorexin system.

"Our laboratory found that theorexin system which is mainly involved in the induction of sleep, is an important factor in maintainingmotivation and themovement in almost terminal patients, "explained Dr. Daniel L. Marks M.D. PHD.

So the drugs that were initially developed to treat sleep disorders , like narcolepsy, now have the potential to restore energy in the chronic patients .

Dr. Daniel Marks concluded that there is an opportunity for this discovery to reach the market in a short time, because the role of the orexin in sleep disorders is well known for several years and research around creating drugs that reverse the loss of said neurotransmitter, They are at an advanced stage and about to enter their clinical application.

It will be a matter of waiting for these very useful medicines for the chronically and terminally ill, since they will provide an improvement in their quality of life and their independence.


Video Medicine: Motion Sickness Treatment | How To Stop Motion Sickness (April 2024).